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Molecular Laboratory Technician 3 in Raleigh, NC with Greene Resources

Date Posted: 5/1/2019

Job Snapshot

  • Employee Type:
  • Location:
    Raleigh, NC
  • Experience:
    Not Specified
  • Date Posted:

Job Description

Job Number: 33037

Molecular Laboratory Technician 3

Job Description:

The Center for Newborn Screening, Ethics, and Disability Studies within RTI International's Education and Workforce Development (EWD) division has an immediate opening for a Molecular Laboratory Technician 3. The Center conducts rigorous studies on newborn screening (NBS) systems by developing and implementing testing methods for rare pediatric genetic disorders. This position is full-time (40-hour work week Monday through Friday) and will work with RTI's CLIA-certified clinical laboratory to support screening for rare diseases, including spinal muscular atrophy (SMA) and fragile X syndrome (FXS). The position has pre-analytical, analytical, post-analytical and general responsibilities related to testing, results reporting, and follow-up of abnormal results. The technologist will perform testing on residual newborn dried blood spot specimens, participate in extensive quality assurance activities, perform routine instrument maintenance, assist in writing and periodic revision of technical standard operating procedures (SOPs), and use a laboratory information management system (LIMS) to manage data and report patient results. The position will require use of high-complexity laboratory instrumentation, including real-time PCR and capillary electrophoresis. The position will be initially located at the North Carolina State Laboratory of Public Health (NCSLPH) in Raleigh, NC and will transition to an RTI location in Research Triangle Park, NC.


  • Laboratory Testing -- 80% (Pre-analytic): Retrieve and determine acceptability of specimens submitted for testing based on proper identification, adequacy, and integrity of specimens; Organize specimens using a unique numbering system and worklists specifically designed for the testing methodology. (Analytic): Perform molecular DNA analyses for SMA and FXS; Prepare reagents in a precise manner according to manufacturer's instructions and laboratory SOPs; Ensure proper operation, maintenance, and documentation of all required equipment and instrumentation; Maintain established quality assurance processes throughout all phases of testing. (Post-analytic): Adhere to an established turn-around time (TAT) for test results and timely notification of supervisor for any delays in testing procedure; Enter screening results into the LIMS; Timely notification of supervisor regarding any technical or quality assurance problems encountered during testing (General): Participate in regulatory-required trainings, competency assessments, and proficiency testing programs; Maintain continuing education requirements by attending technical training courses, scientific meetings and seminars; Adhere to practices designed to ensure patient confidentiality; Demonstrate competency in use of laboratory information management system.

  • Quality Assurance and Quality Control -- 10% : Monitor daily performance and maintenance of instrumentation; Document quality control parameters for the laboratory (temperatures, decontamination, handling of hazardous wastes); Ensure QC and QA documents are provided to the General Supervisor in a timely manner.

  • Assisting General Supervisor -- 5% : Prepare and update standard operating procedures (SOP) according to CLIA guidelines; Maintain accurate inventory of lab reagents and supplies and assist the General Supervisor in ordering reagents and supplies when needed.

  • Safety -- 5% : Participate in the required annual laboratory safety programs; Use appropriate personal protective equipment (PPE) and engineering controls; Ensure work stations comply with health and safety regulations of the laboratory; Maintain good laboratory practice (GLP); Ensure all instruments and specimens are properly handled; Demonstrate a strong work ethic with ability to pay attention to detail; Annually review and attest to the laboratory safety manuals.

Education Requirements:

  • Must have a background in one or more of the following subjects: biology, chemistry, biochemistry, genetics and physics. Bachelor's Degree in Biology, Biochemistry or Related Life Science; or associate degree in medical technology from accredited institute and 2 years of experience; or completion of certified laboratory assistance courses in medical technology with 3 years of experience.

Desired Background/Skills:

  • Experience in troubleshooting high complexity laboratory instrumentation.

  • At least 1 year of molecular testing experience working in a clinical diagnostic laboratory or public health laboratory.

  • Knowledge of rare genetic disorders.


  • Must have experience in conducting nucleic acid extraction and PCR processes.

  • Must have experience in laboratory data interpretation and analysis.

  • Must have general knowledge of CLIA requirements, OSHA, and HIPAA.

  • Must have knowledge of practices and procedures associated with a Biosafety level 2 laboratory.

  • Must have knowledge of laboratory equipment instrumentation and terminology of medical laboratory science.

  • Must have strong mathematical skills to perform calculations and interpret and correlate data.

  • Must have computer skills that include knowledge of Windows, Microsoft Office, e-mail and internet capabilities.

  • Must have a good understanding of the basic components of a laboratory quality assurance program including proficiency testing and quality control standards.

  • Must have organizational skills that allow coordination of multifaceted testing activities including simultaneous performance of several assays while adhering to the strict timing schedule of each test.

  • Must be capable of understanding and following complex oral and written instructions and instructing others in complex technical procedures

  • Must be able to express oneself clearly verbally and in writing. Position requires the ability to write or update Standard Operating Procedures (SOP) for testing methodology.

  • Must not have any predisposing conditions that would render employee susceptible to infectious disease, i.e. must not be immunologically compromised. All work performed in this laboratory involves human clinical specimens which are considered to be potentially infectious. An immunocompromised person would be at increased risk of infection from infectious agents.

  • Must have above average physical/manual dexterity, as the test procedures require the use of equipment that requires physical coordination. A lack of physical/manual dexterity could result in an accident that may compromise the safety of the individual and other laboratory employees.

  • Must be aware of the hazards of working with potentially infectious materials and must know the appropriate precautions to take to avoid infection.

  • Excellent attention to details

  • To qualify, applicants must be legally authorized to work in the United States and should not require now, or in the future, sponsorship for employment visa status

Other Information:

  • Greene Resources is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.